There was a significant ~ tenfold decrease in the p65+ Th1/Th2 ratio in PBMCs from NP women in response to P plasma compared to NP plasma (p = 0.02), and a ~ 15-fold increase in response to IUGR plasma compared to P plasma (p = 0.02) (Fig. 5B). The gene discussed is RELA; the disease is fetal growth restriction.