RELA and fetal growth restriction: To assess whether changes in p65 regulation underlie the observed changes in Th1 and Th17 subsets during normal and IUGR pregnancies, the proportion of p65+ T-cell subsets was assessed using the gating strategy outlined in Fig. 4A. Similar to the basal T-cell subsets, percentage of p65+ Th1 cells was decreased in P when compared to NP (p = 0.04), but not IUGR (p = 0.008; Fig. 4B).