Comparison of the transcriptomes of BBN-induced tumors with subtypes from Cancer Genome Atlas (TCGA) human tumors (n = 408) and known luminal bladder cancer model Upk3a-CreERT2; Trp53L/L; PtenL/L; Rosa26LSL-Luc (UPPL) tumors and controls reveal that the K5VP16;Pparg mutant lesions co-clustered with luminal and luminal Papillary TCGA samples, which express a set of markers including Pparg, Foxa1, Krt18, and Krt20 (Supplementary Fig. 3e). This evidence concerns the gene PPARG and urinary bladder cancer.