Likewise, neither the formation of cytosolic puncta positive for LC3 (Fig. 3i, j), the colocalization of LC3+ autophagosomes with LAMP1+ lysosomes (Fig. 3k, l) nor Beclin1 (Fig. 3m) was found in HPV( + ) HNSCC cells treated with YOK1104. This evidence concerns the gene MAP1LC3A and head and neck squamous cell carcinoma.