Tumor growth rates of murine lymphoma (EL4) and pancreatic adenocarcinoma cell lines (Panco) were significantly higher in HDAC11 knock out C57BL/6 mice [46], and myeloid-derived suppressor cells (MDSCs) isolated from HDAC11 knock out mice seem more suppressive than the WT MDSCs. The gene discussed is HDAC11; the disease is neoplasm.