Some scholars also used Western blot to detect the expression of STAT3 in cholesteatoma and retroauricular skin and found that the expression of STAT3 in cholesteatoma was significantly higher than that in retroauricular skin, suggesting that the upregulation of STAT3 is related to the high proliferation of cholesteatoma epithelial cells [13,14]. The gene discussed is STAT3; the disease is cholesteatoma.