Our study also showed that EGF regulate CXCL14 transcription, and that CXCL14 is inversely correlated with YB-1 in prostate cancer cells (Figure 3c and Figure 6), suggesting a possible mechanism of YB-1 regulation in the cell cycle and in apoptosis in prostate cancer. This evidence concerns the gene CXCL14 and Familial prostate cancer.