Cytokine profiling of COVID-19 samples mainly with patients admitted in the intensive care unit has shown an increase in IL-2, IL-7, GM-CSF, IFN- γ inducible protein 10 (IP-10; CXCL10), MCP-1, MIP-1, and TNF- α [69] which could cause viral-induced hyper-inflammation [69,70]. Here, CSF2 is linked to COVID-19.