Figure 3C,D shows that R-405 administration to established LLC1-PSMA tumors caused a complete inhibition of tumor growth and subsequent tumor regression (complete response, CR, in 100% of the mice). Figure 3E shows the highly significant difference in tumor size at d 21 between untreated and R-405-treated mice. The Kaplan-Meyer survival curve mirrored this huge difference (Figure 3F). This evidence concerns the gene FOLH1 and neoplasm.