Finally, we observed a positive correlation between intrahepatic CCR5+ frequency and liver fibrosis in both monoinfected (CD4: r = 0.69 p = 0.005; CD8: r = 0.65 p = 0.01; Figure 4B) and coinfected patients (CD4: r = 0.92 p = 0.0001; CD8: r = 0.85 p = 0.0001; Figure 4A). Here, CCR5 is linked to Hepatic fibrosis.