CD4 and COVID-19: In addition, along these lines, the U.S. Centers for Disease Control and Prevention (CDC) has concluded [29] that people with HIV who are on effective HIV treatment have the same risk for developing COVID-19 as people who do not have HIV, although the risk for people with HIV getting very sick is greatest for those who have a low CD4 T-cell count and are not on effective HIV treatment such as with ART.