In another study, C57BL/6 mice with murine ovarian surface epithelial carcinoma (MOSEC) received a prime immunization of SFV-OVA followed by boost vaccination with vaccinia virus expressing OVA (VV-OVA), which elicited OVA-specific CD8+ T cell immune responses and enhanced anti-tumor activity [159]. Here, CD8A is linked to neoplasm.