In the multivariable model, age, household registration, education, occupation, the presence of confirmed and suspected family cases, willingness to undergo hepatitis B vaccination, and knowledge that vaccination is an effective way to prevent and control HBV were associated with hepatitis B vaccination coverage rates (Table 2) compared with age group of 1–14, 15–24 (OR = 0.05; 95% CI, 0.02–0.14), 25–34 (OR = 0.05; 95% CI, 0.02–0.14), 35–44 (OR = 0.04; 95% CI, 0.01–0.13), 45–54 (OR = 0.02; 95% CI, 0.01–0.07), 55–64 (OR = 0.01; 95% CI, 0.00–0.04), 65+ (OR = 0.01; 95% CI, 0.00–0.04). The gene discussed is PPIB; the disease is Hepatitis.