MORC2 and developmental delay, impaired growth, dysmorphic facies, and axonal neuropathy: MORC2 missense is also considered a causing factor of developmental delay, impaired growth, dysmorphic facies and axonal neuropathy (DIGFAN; OMIM 619090), and CMT2Z and DIGFAN often overlap in their clinical symptoms (Guillen Sacoto et al., 2020).