Within this shared run, four genes were detected: IGHM (Immunoglobulin heavy constant Mu), MKRN3 (Makorin finger protein 3), MAGEL2 (MAGE family member L2) and NDN (Necdin), located upstream of the Prader-Willi syndrome (PWS) region. The gene discussed is MAGEL2; the disease is Prader-Willi syndrome.