CD40LG and viral infectious disease: In the 2010s, a major dengue epidemic has not been documented in the country, but a seroprevalence study on 376 blood samples collected in 2009–2013 from febrile, symptomatic patients without malaria or yellow fever showed DENV IgM and/or immunoglobulin G (IgG) by enzyme-linked immunosorbent assay (ELISA) (which detects all 4 serotypes), suggesting that dengue fever may be one of the important causes of febrile illness in the country [53].