ADAR and Zika virus infectious disease: Beyond the immediate implications for viral fitness or long-term evolutionary consequences in viral genomes, we also need to consider the role of infection-triggered dysregulation of ADAR editing as a factor in neurodevelopmental and neurodegenerative sequelae of viral infections, such as those observed in ZIKV infections (Piontkivska et al. 2017, 2019), or in mouse models of maternal immune activation (Tsivion-Visbord et al. 2020).