Indeed, SEMA3A, SEMA3B, SEMA3D, and SEMA3F are thought to inhibit integrin function and thus result in anti‐angiogenic effects.[25] SEMA3E has been shown to inhibit tumor angiogenesis, while SEMA4D, SEMA5A, and SEMA6A promote angiogenesis.[25] SEMA3E has also been studied in relation to VEGF regulation, as part of a possible feedback mechanism.[34]. Here, SEMA3E is linked to neoplasm.