Moreover, exogenous administration or NGF has been recently demonstrated to accelerate regrowth and remyelination after peripheral nerve injuries by promoting degenerative nerves collapse and myelin debris clearance.[177] Slimily, NGF has been associated with PAD.[178] Increased levels of NGF have been reported in limb ischemic muscles with strong similarity in terms of the time‐course with increased HIF‐1α levels. The gene discussed is HIF1A; the disease is peripheral arterial disease.