DCC and colorectal cancer: Robo levels were suggested to increase in axons that have crossed the midline, enhancing their responsiveness to Slit, and decreasing Deleted in Colorectal Cancer (DCC) signaling through Netrin‐1.[33] DCC can act both as a chemoattractant and repellent in axonal guidance.[67] Another interpretation focused on Netrin, and its downstream pathway being inhibited.