However, our data reinforces the recommendations by Devreese et al that strongly emphasized that positive tests should be repeated at least 12 weeks after the initial positive test to exclude false positives, clinically unimportant, or transient antibodies.30Based in our data, we can add to this recommendation that all laboratory repetitions should include complete APS profile, that includes LAC, aCL IgG, aCL IgM, aβ2GPI IgG, and aβ2GPI IgM. The gene discussed is ACLY; the disease is autoimmune polyendocrinopathy.