PAS staining showed that Srb1/Ldlr-/- mice developed intraglomerular foam-like lesions that were further identified as Oil-red O (ORO)-positive lipoprotein deposition reminiscent of lesions observed in human lipoprotein glomerulopathy (LPG), which were not seen in control Ldlr-/- mice (Figure 3C). Here, LDLR is linked to lipoprotein glomerulopathy.