In the same context, a multicenter comparative study of several biomarkers reported that sCysC was the best diagnostic biomarker of AKI in comparison to both urinary N-acetyl-β-D-glucosaminidase and albumin/creatinine ratio, as AUC increased with the progression and severity of AKI (AUC for AKI and severe septic AKI was 0.738 and 0.839). The gene discussed is ALB; the disease is acute kidney injury.