Based on the CCLE database, we verified that the mRNA expressions of the four hub genes (COL8A1, SPOCK1, AEBP1, and TIMP2) were higher in fibroblast cell lines than those in GC cell lines (Wilcoxon test, all p < 0.001; Figures 9A,B). This evidence concerns the gene COL8A1 and gastric cancer.