In a multicenter, phase III, double-blind clinical trial, patients receiving silybin-phospholipids complex showed significant improvement of aspartate and alanine aminotransferase (AST, ALT), gamma-glutamyl-transpeptidase (GGT), and liver histology, represented by steatosis, lobular inflammation, ballooning, and fibrosis improvement, without increase in body weight (21). Here, GPT is linked to steatosis.