Similar findings derived from the study of MBOAT7 rs641738 (TMC4C/T-T/T) C>T genetic variant were demonstrated to be linked to the risk of NAFLD worsening in a large population study cohort due to its influence on the hepatic phosphatidylinositol acyl-chain remodeling (15). Here, MBOAT7 is linked to metabolic dysfunction-associated steatotic liver disease.