NLRP3 and enthesitis-related juvenile idiopathic arthritis: In our recent study in patients with ErA, we assessed the methylation levels of the TLR4, CXCR4, NLRP3, and PTPN12 gene promoter, as well as the expression of several non-coding microRNAs (miR-150, miR-146a, miR-181a and miR-223) with reported interactions with the specific genes we were interested in.