Moreover, the activation or suppression of specific miRNA families is the mechanism by which oncogenes such as epidermal growth factor receptor (EGFR) and MET or tumor suppressor genes such as phosphatase and tensin homolog deleted on chromosome 10 (PTEN), adenomatous polyposis coli (APC), and breast cancer type 1/2 (BRCA1/2) induce or inhibit oncogenesis (Zhang et al., 2007; Lee and Muller, 2010). The gene discussed is APC; the disease is cancer.