For example, decreases in neocortical myelin development and myelin-related gene expression resulting in dysregulated CNP and myelin-associated protein (MAG) levels have been observed in patients with schizophrenia (SZ) (Hakak et al., 2001; Dracheva et al., 2006; McCullumsmith et al., 2007; Mitkus et al., 2008). This evidence concerns the gene CNP and schizophrenia.