HMGCR and ankylosing spondylitis: After adjusting the observed association for 25-hydroxyvitamin D level and smoking in the multivariate analyses, the odds ratio for ankylosing spondylitis per change in HMGCR score scaled to a 1 mmol/L decrement in LDL cholesterol levels was 0.12 (95% CI, 0.04–0.39) (Table 3).