Contradictorily, the group of Chang illustrated that myofibroblast stromal cell line WPMY-1 with AR siRNAs could suppress the cell invasion of PCa cells in the coculture system (Niu et al., 2008), and the group of Gross described that reduction of AR in CAFs with antisense oligonucleotide (ASO) dramatically suppressed CAF-promoted PCa growth in vitro and in vivo (Liao et al., 2017). This evidence concerns the gene AR and posterior cortical atrophy.