IL15 and posterior cortical atrophy: By using the coculture system, Galustian et al. confirmed that PCa cells had a stronger ability to enhance IL-15-mediated expansion and cytotoxicity of NK cells than non-cancerous cell lines (PNT2 and WPMY-1) (Sakellariou et al., 2020), suggesting that the human body applies a protective strategy against PCa by activating NK cells.