Meanwhile, the AR/FlnA complex also triggered the activation of focal adhesion kinase FAK, Rac1, and paxillin via recruiting integrin beta 1, promoting cell migration of NIH3T3, HT1080 cells, and PCa-derived fibroblasts (Castoria et al., 2011; Di Donato et al., 2021). The gene discussed is FLNA; the disease is posterior cortical atrophy.