Here, we detected the altered level of GGA1 (Figure 1), a Golgi protein that controls APP processing (von Arnim et al., 2006) and Golgi alterations (Figure 5C), suggesting that Aβ accumulation (a known hallmark in different neurodegenerative diseases) might be involved in cellular perturbations in DNAJC3mutcells. The gene discussed is APP; the disease is neurodegenerative disease.