Fan et al. (2020) found that upregulation of lncRNA ZFAS1 could promote lung adenocarcinoma progression by sponging miR-1271-5p and upregulating FRS2. Chen et al. (2019) found that miR-1271-5p could inhibit cell proliferation and induce apoptosis in acute myeloid leukemia by targeting ZIC2. Here, FRS2 is linked to lung adenocarcinoma.