Our findings indicate that a high expression of different co-DEGs was correlated with a low glomerular filtration rate in kidney disease samples (IL10RA, HLA-DPA1, r = −0.490, p < 0.001; IRF8, HLA-DRA, r = −0.500, p < 0.001; HLA-DPB1, r = −0.510, p < 0.001; HLA-DMA, r = −0.480, p < 0.001) (Figure 7A). Here, IRF8 is linked to kidney disorder.