Regarding the underlying mechanism, Ding et al. (87) found that high expression of G-protein alpha-subunit (GNAS) promotes lipopolysaccharide-induced HCC cell growth and invasion by interacting with signal transducer and activator of transcription 3 (STAT3) in an m6A-YTHDF1-dependent manner. The gene discussed is STAT3; the disease is hepatocellular carcinoma.