For example, the GSH precursor N-acetylcysteine can reduce the effect of ROS in Acute myeloid leukemia stem cells (AMLSCs), which resists the niclosamide antineoplastic and apoptotic effect through inhibition of TNFα-induced nuclear factor (NF)-κB activation and increase of the intracellular ROS levels (107). Here, TNF is linked to acute myeloid leukemia.