The expression of TOX4 in AML-M2 (median: 2.25) and AML-M5 (median: 2.13) patients maintained an upward trend compared with the HI group (median: 1.95, P = 0.036, P = 0.034); however, there was no statistically significant difference between the AML-M3 and HI groups (Figure 2C). This evidence concerns the gene TOX4 and acute myeloid leukemia.