As shown in Figure 1, by using qRT-PCR and Western blot analysis, the results revealed that the expression levels of E6/G6PD protein (Figures 1A, B) and G6PD mRNA (Figure 1C) in cervical cancer groups were significantly higher than that of non-cancer control groups [HPV E6 protein: degree of freedom (df) = 62, F = 441.372, p = 0.000; G6PD protein: df = 62, F = 821.223, p = 0.000; G6PD mRNA: df = 62, F = 968.337, p = 0.000]. This evidence concerns the gene G6PD and cancer.