These results suggest that TIICs are associated with the prognosis of patients with NPC, especially activated CD8+ T cells, central memory CD4+ T cells, effector memory CD8+ T cells, immature dendritic cells, macrophages, myeloid-derived suppressor cells (MDSCs) and T follicular helper cells, which were statistically different in both datasets. This evidence concerns the gene CD8A and nasopharyngeal carcinoma.