However, MMP-3 and MMP-7 levels were decreased by CBD more in UVB irradiated psoriatic KCs than in UV-irradiated healthy cells, while the MMP-1 and MMP-2 expression was reduced by CBD significantly more in UV-irradiated healthy cells as compared with the reaction of psoriatic KCs (Figure 4). The gene discussed is MMP1; the disease is dry eye syndrome.