It shows that the levels of serum sTREM-1 and CXCL-16 in children with Mycoplasma pneumonia are increased, and the levels of serum sTREM-1 and CXCL-16 are closely related to the condition of children with Mycoplasma pneumonia. Here, CXCL16 is linked to Mycoplasma pneumoniae pneumonia.