According to analysis, patients with a high FTO level faced notably higher probabilities of stage III + IV and lymph node metastasis (LNM), and CEA was notably bound up with the clinical stage and tumour type of patients with a high CYFRA21-1 level (all P < 0.05; Tables 1, –3). This evidence concerns the gene CEACAM5 and metastatic malignant neoplasm in the lymph nodes.