Adiponectin, upon binding to its receptors, increases oxidation of fatty acids and glucose uptake via activating the peroxisome proliferator-activated receptor-gamma (PPAR-γ) ligand pathway [14], thus possessing potential for the treatment of diabetic complications [15] with vascular disorders [16], whereas PPAR-γ on activation directly impacts the adiponectin gene transcription [17]. This evidence concerns the gene ADIPOQ and vascular disorder.