MYBPC3 and hypertrophic cardiomyopathy: Pathogenic splice acceptor variant c.26-2A > G in MYBPC3 (rs376395543) is associated with hypertrophic cardiomyopathy (VCV000042644.10) and is observed in six copies in non-Finnish Europeans (frequency 5.2 × 10–5) and one allele copy in Latino Americans.