Based on the data on lncRNA expression profiles extracted from TCGA, the present study showed that aberrant expression levels of LINC01614, LINC01537, LINC01210, OVAAL, LINC01446, CYMP-AS1, and SCAT8 may associated with OS in GC patients and these seven lncRNAs could be used to construct a prognostic signature in GC. The gene discussed is CYMP-AS1; the disease is gastric cancer.