CXCL10 and type 1 diabetes mellitus: Mice lacking CXCR3 and infected with lymphocytic choriomeningitis virus-WE strain (LCMV-WE), an established model to study T1D, exhibited a delay in insulitis, while overexpressing CXCL10 in mouse islets accelerated LCMV-induced diabetes (127, 137, 138).