Autologous monocyte-derived dendritic cells (DCs) from NPC patients pulsed with HLA-A11-, -A24-, or -B4-restricted LMP2 epitopes boosted EBV-specific CD8+ T-cell responses in nine of 16 patients, and induced partial tumor regression in two patients (191). The gene discussed is PSMB9; the disease is nasopharyngeal carcinoma.