Assessed: 5/5 = BP, body weight, FBG, fasting insulin, and insulin resistance index, TG, HDL-C, LDL-c. Met: 5/5 = Reduction in body weight, BP, FBG, fasting insulin and insulin resistance index, TG levels reduced, and HDL-c increased. LDL-C reduced. This evidence concerns the gene INS and Insulin resistance.