Our findings harmonize with previous studies that revealed a rapid amplified GFAP expression in various animal models of epilepsy, including PTZ (Torre et al., 1993; Sedky et al., 2017), electrical kindling (Stringer, 1996; Miyazaki et al., 2003), and kainic acid (Bendotti et al., 2000; Choi et al., 2003; Glushakova et al., 2012; Lee et al., 2012). This evidence concerns the gene GFAP and epilepsy.