The KEGG enrichment analysis revealed that the chief pathways were concentrated in the AGE-RAGE signaling pathway in the pathogenesis of diabetes and its complications, the TNF signaling pathway, the PI3K–Akt signaling pathway, pathways in cancer, the mitogen-activated protein kinase (MAPK) signaling pathway, and some related to thyroid cancer. The gene discussed is RENBP; the disease is thyroid cancer.