MAPT and Alzheimer disease: According to the cell culture study of Belkacemi and Ramassamy, a mixture of anthocyanins and proanthocyanidins could beneficially affect various mechanisms involved in AD development such as through inhibition of Aβ toxicity and tau phosphorylation, prevention of oxidative stress, and amelioration of mitochondrial dysfunction (Belkacemi and Ramassamy, 2016).