PVALB and central nervous system cancer: In the latest years it has been demonstrated that, while pyramidal cell activity promotes proliferation in both murine and patient-derived high-grade gliomas (Venkatesh et al., 2015, 2017; Tantillo et al., 2020b), the selective stimulation of parvalbumin-positive interneurons elicits the opposite effect in glioma-bearing mice (Tantillo et al., 2020b).