BDNF and multiple sclerosis: Drugs that increase the levels of BDNF such as glatiramer acetate, known as a multiple sclerosis immune modulator, could be used to recover neuronal function by stimulating the serotonin receptor 7 in conjunction with inhibiting PTP1B, which blocks the TRKB receptor of BDNF (Krishnan et al., 2015; Napoletani et al., 2021; Vigli et al., 2021).