The results showed that in comparison to murines treated with normal A172 cells and GSC23 exosomes, tumor weight/volume readings were drastically reduced among tumor-carrying murines subjected to A172 and circ-Serpine2-deficient exosomes (Fig. 7A, B, D), with tumor weight analyses demonstrating statistical significance (P < 0.05). The gene discussed is SERPINE2; the disease is neoplasm.